Shirley V. Wang, PhD, ScM

Dr. Wang is an Associate Professor at Brigham and Women’s Hospital, Harvard Medical School. Her research is focused on 1) developing innovative, non-traditional analytic methods to understand the safety and effectiveness of medication use in routine clinical care as well as 2) facilitating appropriate use of complex methods for analyzing large observational healthcare data. She has received several awards from international societies for her methods work and is currently PI on multiple NIH R01s and FDA contracts.
She leads the Meta-Research in Pharmacoepidemiology program, with recent projects aimed at improving the transparency, reproducibility and robustness of evidence from healthcare databases (www.repeatinitiative.org) and informing when and how real-world evidence studies can draw causal conclusions to inform regulatory or other healthcare decision-making (www.rct-duplicate.org), through a series of large scale emulation projects offering insights into what types of clinical questions can be answered with real-world data and which methods are the most robust.
Dr. Wang co-led the 1st and 2nd joint task forces for the International Society of Pharmacoepidemiology (ISPE) and the International Society for Pharmacoeconomics and Outcomes Research (ISPOR) focused on real-world evidence for healthcare decision-making. She is a former Board member of ISPE and currently serves as an elected member of the Patient Centered Outcomes Research Institute (PCORI) Methods Committee and Lead Epidemiologist for the FDA’s Sentinel Innovation Center.